introduction:  laser  interstitial  thermotherapy  (litt)  is  an  internal  ablation  therapy  method  consisting of a percutaneous or intraoperative insertion of laser fibers directly into the liver tumor with  maximum diameter of 5 cm. in this treatment method, there isn’t any general information about the  relationship  between  increasing  the  exposure  power,  coagulation  and  carboniza...

Introduction:  Laser  interstitial  thermotherapy  (LITT)  is  an  internal  ablation  therapy  method  consisting of a percutaneous or intraoperative insertion of laser fibers directly into the liver tumor with  maximum diameter of 5 cm. In this treatment method, there isn’t any general information about the  relationship  between  increasing  the  exposure  power,  coagulation  and  carboniza...

OBJECTIVE To characterize tissue destruction after CO(2) laser-ablation of the vocal cords with the use of optical coherence tomography (OCT). STUDY DESIGN AND SETTING OCT was used to image fresh porcine vocal cords after laser ablation. OCT and histology estimates of the ablation crater dimensions and the depth of thermal injury were obtained. RESULTS The vocal cord substructures up to 2.2...

BACKGROUND Clinical treatment of cardiac arrhythmia by radiofrequency ablation (RFA) currently lacks quantitative and precise visualization of lesion formation in the myocardium during the procedure. This study aims at evaluating thermal dose (TD) imaging obtained from real-time magnetic resonance (MR) thermometry on the heart as a relevant indicator of the thermal lesion extent. METHODS MR t...

BACKGROUND Recently, we demonstrated the feasibility and safety of circular electroporation ablation in porcine pulmonary vein ostia, but the relationship between the magnitude of the application and lesion dimensions is still unknown. METHODS AND RESULTS An in vivo porcine study was performed on left ventricular epicardium submerged under 10 mm of blood, using devices that mimic a 20-mm-diam...

PURPOSE Ultrasound (US)-guided high intensity focused ultrasound (HIFU) has been proposed for noninvasive treatment of neuropathic pain and has been investigated in in-vivo studies. However, ultrasound has important limitations regarding treatment guidance and temperature monitoring. Magnetic resonance (MR)-imaging guidance may overcome these limitations and MR-guided HIFU (MR-HIFU) has been us...

BACKGROUND Radiofrequency (RF) ablation causes thermal mediated irreversible myocardial necrosis. This study aimed to (i) characterize the thermal characteristics of RF ablation lesions with high spatial resolution using a thermochromic liquid crystal (TLC) myocardial phantom; and (ii) compare the thermochromic lesions with in vivo and in vitro ablation lesions. METHODS AND RESULTS The myocar...

background: usual dosage  of morphine  (10 mg/kg) induces  analgesia  and ultra-low dose (uld) of morphine (1 μg/kg); hyperalgesia, and  c-fibers are also bearing  μ- opioid receptors; here the importance  of c-fibers on pain and  morphine   induced  analgesia/hyperalgesia  is questioned   and  investigated    using   pain   evaluation methods and infant capsaicin treating  for c-fibers lesioni...

Surface magnetoelastic waves are coupled elastic and magnetic excitations that propagate along the surface of a magnetic material. Ultrafast optical techniques allow for a non-contact excitation and detection scheme while providing the ability to measure both elastic and magnetic components individually. Here we describe a simple setup suitable for excitation and time resolved measurements of h...